Proinflammatory Cytokines

Proinflammatory Cytokines in Peritonitis

RATIONALE We performed this study with the purpose of revealing different aspects of the systemic inflammatory response syndrome in peritonitis. OBJECTIVES The aim of the presentation was to make a research on some of the immune response mediators in secondary peritonitis and to observe their capacity to anticipate the evolution towards septic complications. METHODS AND RESULTS We have unde...

Nociceptor Sensitization by Proinflammatory Cytokines And Chemokines

Cytokines are small proteins with a molecular mass lower than 30 kDa. They are produced and secreted on demand, have a short life span and only travel over short distances if not released into the blood circulation. In addition to the classical interleukins and the chemotactic chemokines, growth factors like VEGF or FGF and the colony stimulating factors are also considered cytokines since they...

An Excess of the Proinflammatory Cytokines

Proinflammatory cytokines and glutamate in acute stroke.

Proinflammatory Cytokines and Glutamate in Acute Stroke To the Editor: I have with great interest read the article, “Proinflammatory Cytokines and Early Neurological Worsening in Ischemic Stroke,” by Vila et al.1 Bearing in mind the complexities of interleukin (IL)-6 effects, I would like to ask the authors the following questions: Are the patients included in this study the same patients as in...

Central proinflammatory cytokines and pain enhancement.

Enhanced pain is a component of the 'sickness response' which is an evolutionarily adaptive constellation of responses that enhance the survival of the host. Proinflammatory cytokines mediate these sickness behaviors, and whether proinflammatory cytokines are involved in exaggerated pain has become an intriguing question. Studies suggest that spinal cord glial cells (astrocytes and microglia) a...